How many years after the onset of symptoms does early-onset Alzheimer disease typically lead to death?

Early-onset Alzheimer’s disease, which typically affects individuals before the age of 65, often presents a rapid progression of symptoms compared to late-onset forms of the disease. Individuals with early-onset Alzheimer’s usually live for about 10 to 15 years after the initial onset of symptoms. This timeframe can vary significantly across individuals based on various factors such as genetics, overall health, and the level of care received.

The progression of the disease involves a decline in cognitive and functional abilities, leading to increased dependence on caregivers and ultimately resulting in serious health complications that contribute to mortality. Therefore, the 10 to 15 years timeframe is representative of the typical course of the disease and reflects a consensus in scientific literature on the expected life expectancy following the onset of symptoms in early-onset cases.